Seward Rutkove’s lab focuses on a broad range of neuromuscular disorders, including:
- Amyotrophic lateral sclerosis: recent novel study is the ALS Testing through Home-Based Outcome Measures (ALS AT HOME). To learn more, please visit: www.ALS-AT-HOME.org.
- Muscular dystrophy.
- Spinal muscular atrophy.
- Polyneuropathies, including diabetic neuropathy.
- Inflammatory myopathies.
- Localized nerve problems/compressions.
Much of our research involves the application of electrophysiological measures, imaging modalities, and innovative bioengineering approaches to diagnose and treat these disorders. These techniques include electrical impedance myography, quantitative ultrasound, magnetic resonance imaging, and nerve and muscle excitability techniques. We are also interested in studying mechanisms of disease pathogenesis and testing new therapeutic agents that can improve function and health. Some of our longer term goals include developing novel, powerful biomarkers to assist with disease diagnosis, the assessment of progression, and the effect of therapy.