OUR TEAM

Seward Rutkove, M.D.  

Email: srutkove@bidmc.harvard.edu

Dr. Rutkove is Professor of Neurology, Harvard Medical School and serves as Chief of the Division of Neuromuscular Disease in the Department of Neurology at Beth Israel Deaconess Medical Center. He received his medical degree from Columbia University’s College of Physicians and Surgeons, and his bachelor magna cum laude from Cornell University, College of Arts and Sciences.

        

Dr. Rutkove’s research focuses on the application of innovative techniques for the assessment of neuromuscular disease with an emphasis on electrical impedance and ultrasound methodologies.  This work has been supported by numerous grants from the National Institutes of Health, NASA, and multiple foundations, and has resulted in well over 150 peer-reviewed publications.  He is currently serving as an associate editor of neuromuscular disorders for Annals of Neurology. Dr. Rutkove is also a co-founder of Myolex, Inc, a San Francisco-based company commercializing muscle impedance tools for clinical care and consumer use.  In 2011, he was awarded the Biomarker Challenge Prize from the non-profit foundation Prize4Life, Inc for his work demonstrating that electrical impedance measurements of muscle could speed clinical therapeutic studies in amyotrophic lateral sclerosis.

 

Physicians

 

Courtney E. McIlduff, M.D., MMSc. 

Clinical Neurophysiology

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Jim S. Wu, M.D. 

Radiologist

Email: jswu@bidmc.harvard.edu

Dr. Wu was born in Hualien,Taiwan and moved to South Texas at a young age.  He graduated from the Massachusetts Institute of Technology in 1994 with a BS in Biology and Concentration in the History of Art and Architecture. After graduating from Baylor College of Medicine in Houston, TX (1999), he then completed an internal medicine internship at the Lahey Clinic in Burlington, MA (2000). He completed his Diagnostic Radiology Residency (2004) and Musculoskeletal Imaging Fellowship (2005) at Yale/New Haven Hospital.  Dr. Wu has been on the musculoskeletal imaging staff at BIDMC since 2005.  His clinical and research interests relate to musculoskeletal neoplasms, image guided interventions, and developing novel techniques to image muscle disorders.

He has authored over 70 scientific articles/books/book chapters, has given numerous national/international lectures, and is a reviewer for several journals. Dr. Wu also has a strong interest in medical education and served as the Radiology Residency Program Director from 2009-2011. He has won several teaching and mentorship awards including the departmental faculty teaching award (2006, 2009), Harvard Medical School Young Mentor Award (2012) and Harvard "Excellence in Medical Student Teaching" Award (2013, 2016). He lives in Lexington, MA with his wife and 2 children.

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Neurology Instructor

Benjamin Sanchez, Ph.D.

Email: bsanchez@bidmc.harvard.edu

Education history: Benjamin Sanchez received a B.S. in Telecommunication Engineering, a B.S., a M.Sc. with honors (3rd top-ranking student) and a Ph.D. in Electronic Engineering at Universitat Politècnica de Catalunya (UPC), Barcelona, Spain, in 2006, 2008, 2009 and 2012 respectively. After finishing his Ph.D., he was Visiting Scientist at the Department of Fundamental Electricity and Instrumentation at Faculty of Engineering in Vrije Universiteit Brussel, Brussels, Belgium, in 2012; and the Automatic Control Lab at KTH-Royal Institute of Technology, Stockholm, Sweden, in 2013. Since January 2014, he has been a Postdoctoral Fellow at Harvard Medical School.

Benjamin’s research interest is the measurement and identification of electrical bioimpedance. He is specifically interested in studying the potential of joining standard neuromuscular electrophysiological techniques with impedance-based techniques for the evaluation of diseased muscle. His major contribution to science has been the development of novel time-variant techniques and tools for measuring impedance using a multidisciplinary approach that integrates control theory, system identification and experiment design.

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Lab Manager

Janice A. Nagy, Ph.D.                                               

Email: jnagy@bidmc.harvard.edu

Education History: Received a Ph.D. in Biophysical Chemistry from   Cornell  University; Postdoctoral Training at Dana Farber Cancer Institute and the Pathology Department at Harvard Medical School;   Investigator at the Center for Vascular Biology Research at Beth Israel   Deaconess Medical Center with a focus on preclinical models of VEGFA-induced pathological angiogenesis, lymphangiogenesis and vascular hyperpermeability.

I Joined the lab in July 2016; Responsible for the daily operations of the laboratory including both administrative duties and direct involvement in research endeavors of the lab; ensures compliance with lab safety guidelines; oversees lab equipment needs, inventory and the ordering of lab supplies; supervises mouse colony management. Areas of research include the application of electrophysiological techniques including electrical impedance myography (EIM) for the assessment of neuromuscular diseases in preclinical models of amyotrophic lateral sclerosis (ALS), spinal muscle atrophy (SMA), Muscular Dystrophy, Muscle Injury, Disuse, and Sarcopenia.

Personal interests: Gardening; Cooking; Arts & Crafts 

Future Goals: Make more time for family, friends and hobbies.

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 Post-doctoral Research Fellows

Marie Mortreux, Ph.D.

Email: mmortreu@bidmc.harvard.edu

Education History: Universite Paris Diderot Paris 7, France : B.Sc, M.Sc, PhD in physio-pathology

I obtained her B.Sc and M.Sc in genetics and life sciences, which were combined to laboratory work in l'Universita Degli Studi di Padova, Italy and the University of California San Francisco, USA. I then received my Ph.D. in physio-pathology, experimenting a novel therapeutic approach (using the olfactory bulb) to treat obesity and type 2 diabetes, in April 2016, and joined the laboratory in September as a post-doctoral fellow.

I will take part in the animal projects regarding muscular atrophy during spaceflight and neuromuscular diseases.

Personal interests: I am highly interested in several animal models for human diseases and specialized in stereotactic surgery.

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Hyeuknam Kwon, Ph.D.

Email: hkwon1@bidmc.harvard.edu

Education History: B.S. and Ph.D. in Mathematics at Yonsei University in 2009 and 2015 respectively.
I joined the lab in October 2016.I earned my Ph.D. in Mathematics at Yonsei University in Feb. 2015. I get involved in: electrical bioimpedance, electrical impedance myography, and studying the potential of joining standard neuromuscular electrophysiological techniques with impedance-based techniques for the evaluation of diseased muscle.

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Bhooma Aravamuthan, M.D., D.Phil.

Email: baravamu@bidmc.harvard.edu

Education history: B.S. in Biochemistry and B.S. in Physiology with Specialization in Bioethics at Michigan State University 2005, D.Phil. at University of Oxford 2008, M.D. at Washington University in St. Louis 2012.

Joined the lab: January 2017

I'm interested in delineating the neuronal injury necessary to cause dystonic cerebral palsy following neonatal hypoxia ischemia. As a part of this research, I'll be characterizing the motor phenotype of a model of rodent hypoxia ischemia in the Rutkove Lab using EMG, functional analyses, and EIM.

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 Clinical Research Fellows

Maria Martucci, M.D.

Email: mmartucc@bidmc.harvard.edu

Education History: Universidad Latina de Panama, Medical Doctor (MD)

I joined the lab in June of 2016 with the objective of contributing in research of Neuromuscular Diseases. After graduating from med-school in Panama in 2011 and working for a couple of years back home, I moved to the US to pursue a carrier in Neurology. The opportunity of working in the Rutkove lab presented to me in a very serendipitously way and opened the door for me to learn about neuromuscular conditions in deeper way. In the lab I'm mostly involve in projects that assess the state of the muscle with different tools that range from ultrasound to electrical impedance myography. This allowed me to be in touch with people that have a wide variety of conditions; from healthy participants to patients in the ICU. Neuromuscular disease research is necessary as the prevalence of these diseases go increcendo and there are still no reliable tools to make their diagnosis, track their progression and allow us to get closer to cures as we understand their pathophysiology better.

Personal interests: My beautiful tiny family, human and animal rights, yoga and meditation, running, game of thrones, global health and public health, playing the ukelele.

Future Goals: I plan to become a clinician scientist neurologist and pursue a MPH in the near future. In the long-run I would love to be a professor and be involved in health politics.

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Hilda Gutierrez

Email: hgutier1@bidmc.harvard.edu

 

 

 

 

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Research Assistants

Kristin Qi, M.S.

Email: kqi@bidmc.harvard.edu

Education History: MS in Bioinformatics and BS in Biomedical Engineering

I joined the lab in May 2016 and I am working on the ALS AT HOME study. On the other hand, I spend time doing data analysis. In the future, I am strongly interested in computational sciences and will pursue the career in data science.

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Rebecca Taylor, B.A. 

Email: taylor4@bidmc.harvard.edu

Education History: Smith College BA in Neuroscience and Biochemistry

I joined the lab in June 2016 after graduating from Smith College. I am a research assistant who conducts experiments in animals and analyzes the data.

Future Goals: I would like to pursue a PHD in neuroscience.

     

Graduate Students

Fu Zhang, Ph.D. candidate

Email: fzhang@bidmc.harvard.edu

Education History: B.S. and M.S. from Xi'an University of Technology, China, in 2012 and 2015 respectively. I am a Ph.D. candidate at Hunan University.

I joined the lab in September, 2017 and I am involved in projects related to electrical bioimpedance and electrical impedance myography. The aspects I am interested in are studies related to fast measurement technology in electrical bioimpedance and electrical impedance myography theory.

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Maria Guasch

Email: mguasch@bidmc.harvard.edu

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Undergraduate Student

Joyce Yang, studies at MIT

Email: jyang12@bidmc.harvard.edu

Currently works on clinical research.

 

 

 

 

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Summer Students

Alison Poussaint 

Worked on hand muscle project.

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Lydia Forti 

Worked on ALS at home project.

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Yun Wang, M.D.

Email: ywang26@bidmc.harvard.edu                            

Education History: 2002-2010 Peking University: Health Science Center 

I'm a visiting research fellow of Dr. Rutkove's lab. I joined the lab in October 2017. I graduated from Peking University Health Science Center​ and obtained my M.D. in 2010. I have been working as a neurologist for more than 7 years. Now I'm doing research in various neuromuscular disorders.

Carmen Shin, Research Assistant

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Adam Pacheck, Research Assistant

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  Jia Li, Postdoc Professional

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Yim Sung, Research Assistant

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Alex Mijailovic, Research Assistant

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